Turmeric (Curcuma longa) is a traditional spice and rhizomatous herbaceous perennial plant of the ginger family native to southern Asia. Its bright yellow-orange color is recognizable in many Indian food dishes. Studies have shown that curcumin, a naturally occurring biologically active group of compounds from turmeric, can function as efficient antioxidants and can help regulate the body’s normal responses after physical exertion. Turmeric’s antioxidant properties are also thought to play a role in supporting tissue health, joint health and cardiovascular function. Resent research has shown that curcumin, which is the main curcuminoid of turmeric, effects intracellular signaling cascades, particularly those involving NF-kappaB and mitogen-activated protein kinases. It has been used in clinical trials to comfort and support to the knee joints.