Longvida® Optimized Curcumin , based on patent pending discoveries from UCLA, is a revolutionary new ingredient for healthy brain aging. Longvida®’s Solid Lipid Curcumin Particle (SLCP) Technology meets all three requirements for bioavailability: solubility, permeability, and stability, as evidenced by therapeutic levels of free curcumin detected in the bloodstream and target tissues. The SLCP technology formulation precisely preserves curcumin particles in a solid lipid base in a way that preserves and protects the curcumin from the harsh environment of the stomach, and allows it to dissolve at the optimal point for absorption in the GI tract. The end result permits maxi mal absorption of the active free form of curcumin.
Curcumin is insoluble in water at neutral and acidic pH, undergoes rapid glucuronidation, and is generally thought to be poorly bioavailable and rapidly excreted. Several human pharmacokinetic studies have only detected curcumin in blood in the inactive glucuronide form. Free curcumin is the only form that has been shown to pass the blood brain barrier .