Meratrim™ is a proprietary plant extract blend for weight management derived from two plants, Sphaeranthus indicus and Garcinia mangostana , traditionally used in Southeast Asian cul ture . Meratrim has been shown in two independent, randomized, double – blind, placebo – controlled clinical studies to significantly reduce body weight, BMI, and waist circumference within 8 weeks when used in combination with a diet and exercise plan† . Meratrim appears to achieve this by modulating the accumulation of fat while simultaneously increasing fat burning † . Toxicological studies on Meratrim have demonstrated a wide margin of safety.
Capsimax™ capsicum extract is a proprietary encapsula ted form of premium, highly concentrated natural capsicum fruit extract manufactured from hot red peppers. Capsaicinoids are a group of compounds which cause the “heat” found in hot peppers. Benefits of capsicum and capsaicinoids in animal and human studies have shown that it helps manage appetite, supports healthy metabolism to burn calories, and helps induce thermogenesis.† Capsimax™ is a patent – pending encapsulated form of premium, highly concentrated natural capsicum extract. Using a proprietary matrix, Capsimax capsicum extract gives users the maximum effectiveness of capsaicinoids without any oral or gastric irritation, thus solving the problem of capsicum compliance.
Zychrome™ is a unique, patent – pending chromium complex consisting of chromium, niacin and L – cysteine (chromium dinicocysteinate). Seventeen chromium complexes were screened in preclinical studies in order to arrive at the complex found in Zychrome™ . In vitro and in vivo studies demonstrated that Zychrome is more efficacious than other forms of chromium in supporting healthy fasting glucose levels, glycated hemoglobin levels (HbA1c), insulin levels , CRP, MCP – 1, ICAM – 1 and oxidative stress levels † . These effects of Zychrome are mediated via the regulation of cell signal transduction pathways associated with insulin function, glucose control and vascular inflammation † . A randomized, double – blind, placebo – controlled clinical study showed that Zychrome significantly modulated the levels of insulin and insulin resistance as well as the inflammatory cytokine TNF and protein carbonyl , an oxidative stress marker. Toxicological studies have demonstrated a wide margin of safety.
This natural extract comes from a tropical fruit grown in several Asian rain forest areas. Research shows that ( – ) hydroxycitric acid helps maintain a healthy balance of hepatic lipogenesis and gluconeogenesis, thus preventing excessive conversion of glucose from dietary carbohydrate into body fat. Research also indicates that ( – ) hydroxycitric acid plays an important role in the regulation of normal appetite. †
Conjugated Linoleic Acid
CLA is a mixture of conjugated dienoic derivatives of linoleic acid from safflower oil. Conjugated linoleic acid is found mainly in meat and dairy foods; however it can also be found in certain vegetable oils. Its presence in human tissue comes not only from dietary sources, but also from in vivo oxidation of linoleic acid. CLA has shown to be beneficial in supporting healthy weight management by maintaining normal fat metabolism and maintaining lean muscle mass in the body. †
Relora ® is a patent – pending combination of two herbal extracts of Magnolia and Phellodendron bark (Asian cork tree). Both herbs have been used in Traditional Chinese Medicine for several hundred years. In a human study, 82% of the participants taking Relora ® agreed with the statement that: “Relora ® helps control irritability, emotional ups and do wns, restlessness, tense muscles, poor sleep, fatigue, and concentration difficulties.” Relora ® was found not to cause sedation, though 74% of the patients had more restful sleep. Additionally, no adverse side effects were reported during the trial. A heal thy weight management program should include strategies to help support stress and anxiety, especially in individuals sensitive to stress – induced eating.
As co – enzymes, the B vitamins are essential components in most major metabolic reactions. They play an important role in energy production, including the metabolism of lipids, carbohydrates, and proteins. B vitamins are also important for blood cells, horm ones, and nervous system function. As water – soluble substances, B vitamins are not generally stored in the body in any appreciable amounts (with the exception of vitamin B 12 ). Therefore, the body needs an adequate supply of B vitamins on a daily basis.